incapacitance meter Search Results


93
UGO Basile S.R.L right contralateral hind limbs
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Right Contralateral Hind Limbs, supplied by UGO Basile S.R.L, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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right contralateral hind limbs - by Bioz Stars, 2026-10
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IITC Life Science incapacitance meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Incapacitance Meter, supplied by IITC Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IITC Life Science iitc incapacitance meter (ic meter)
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Iitc Incapacitance Meter (Ic Meter), supplied by IITC Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BIOSEB Inc static incapacitance meter platform
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Static Incapacitance Meter Platform, supplied by BIOSEB Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BIOSEB Inc incapacitance meter bioseb
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Incapacitance Meter Bioseb, supplied by BIOSEB Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BIOSEB Inc incapacitance meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Incapacitance Meter, supplied by BIOSEB Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IITC Life Science small animal incapacitance meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Small Animal Incapacitance Meter, supplied by IITC Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IITC Life Science non-invasive pain bipedal balance instrument iitc incapacitance analgesia meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Non Invasive Pain Bipedal Balance Instrument Iitc Incapacitance Analgesia Meter, supplied by IITC Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IITC Life Science incapacitance meter tester model-600r
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Incapacitance Meter Tester Model 600r, supplied by IITC Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BIOSEB Inc computerized incapacitance meter system
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Computerized Incapacitance Meter System, supplied by BIOSEB Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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SCHOTT incapacitance meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
Incapacitance Meter, supplied by SCHOTT, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NatureGene Corp incapacitance meter
Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from <t>contralateral</t> DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.
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Image Search Results


Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from contralateral DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.

Journal: Frontiers in Molecular Neuroscience

Article Title: Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels

doi: 10.3389/fnmol.2024.1416148

Figure Lengend Snippet: Neuronal DRG Transduction by vHCA8. IHC was performed with NeuN neuronal antigen expression, and V5 antibody to identify exogenous CA8* peptide expression on D14 after vHCA8*; using three different routes of administration including injection into the knee joint (KJ) (A,D,I) ; rear foot pad ( RFP ) (B,E,I) ; and sciatic nerve (SN) (C,F–I) . About 35–50% of ipsilateral lumbar 4–5 DRG neurons were V5-positive after vHCA8*WT treatment. The percentage of SN V5-positive neurons was higher than that in the KJ and RFP groups. Only about 5% of DRG neurons were V5-positive after vHCA8*MT treatment (G) . There was no V5-positive signal from contralateral DRG (H) . ImageJ version 1.54 was used to count stained cells. Groups were compared using IBM SPSS Statistics version 28 to do Student’s t -test, or ANOVA, followed by Fisher’s protected least significant difference (LSD) test, and these data are presented as mean ± SEM. Statistical significance was p < 0.05. Scale = 100 μm.

Article Snippet: Weight-bearing distribution between the left (MIA) and right (contralateral) hind limbs were tested by the Librae Incapacitance Tester (Ugo Basile) in mice after various treatments.

Techniques: Transduction, Expressing, Injection, Staining

vHCA8*WT reverses MIA-OA-induced decreases in weight-bearing. Male C57BL/6 mice underwent IA KJ injection with 1 mg of monosodium iodoacetate (MIA) on D1 (after Baseline was established) producing hyperalgesia in all mice. Weight-bearing was assessed at about the same time each day as weight (grams) of ipsilateral (treated) limb/weight of ipsilateral limb + weight of contralateral limb (untreated control). On D3 mice were treated with IA KJ injections of either vHCA8*WT at the High-Dose (HD) (1E6 PFU), Mid-Dose (MD) (1E5 PFU) or vHCA8*MT High-Dose (HD) (1E6 PFU) (virus arrow) after weight-bearing assessment. Weight-bearing as measured (grams) dropped starting on D1 after MIA injection in all mice. Weight-bearing increased significantly in mice treated with vHCA8*WT-HD or vHCA8*WT-MD on D27 and D34, respectively, as compared to mice treated with vHCA8*MT-HD. * p < 0.05 for vHCA8*WT-HD vs. vHCA8*MT-HD, # p < 0.05 for vHCA8*WT-MD vs. vHCA8*MT-HD. Data were analyzed for statistical significance between different time points for each group, as compared to Baseline, by one-way analysis of variance (ANOVA) followed by Fisher’s LSD post-hoc test. Repeated measure two-way ANOVA analyses found significant differences in weight distribution between left (OA) and right (contralateral control) hind limbs across all time points [ F (14, 196) = 9.637, p = 3.898E-16]. N = 10 per group.

Journal: Frontiers in Molecular Neuroscience

Article Title: Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels

doi: 10.3389/fnmol.2024.1416148

Figure Lengend Snippet: vHCA8*WT reverses MIA-OA-induced decreases in weight-bearing. Male C57BL/6 mice underwent IA KJ injection with 1 mg of monosodium iodoacetate (MIA) on D1 (after Baseline was established) producing hyperalgesia in all mice. Weight-bearing was assessed at about the same time each day as weight (grams) of ipsilateral (treated) limb/weight of ipsilateral limb + weight of contralateral limb (untreated control). On D3 mice were treated with IA KJ injections of either vHCA8*WT at the High-Dose (HD) (1E6 PFU), Mid-Dose (MD) (1E5 PFU) or vHCA8*MT High-Dose (HD) (1E6 PFU) (virus arrow) after weight-bearing assessment. Weight-bearing as measured (grams) dropped starting on D1 after MIA injection in all mice. Weight-bearing increased significantly in mice treated with vHCA8*WT-HD or vHCA8*WT-MD on D27 and D34, respectively, as compared to mice treated with vHCA8*MT-HD. * p < 0.05 for vHCA8*WT-HD vs. vHCA8*MT-HD, # p < 0.05 for vHCA8*WT-MD vs. vHCA8*MT-HD. Data were analyzed for statistical significance between different time points for each group, as compared to Baseline, by one-way analysis of variance (ANOVA) followed by Fisher’s LSD post-hoc test. Repeated measure two-way ANOVA analyses found significant differences in weight distribution between left (OA) and right (contralateral control) hind limbs across all time points [ F (14, 196) = 9.637, p = 3.898E-16]. N = 10 per group.

Article Snippet: Weight-bearing distribution between the left (MIA) and right (contralateral) hind limbs were tested by the Librae Incapacitance Tester (Ugo Basile) in mice after various treatments.

Techniques: Injection, Control, Virus